HnRNP F (HNRNPF) (NM_004966) Human Recombinant Protein

• Background:

  This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

• Synonyms:

  HNRPF; mcs94-1; OK/SW-cl.23

• Gene ID:

  3185

• UniProt:

  P52597, A0A024R7T3

• Accession Number mRNA:

  NM_004966

• Chromosomal Location:

  10q11.21

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  45.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  HNRNPF

• Species:

  Human

• Protein ID:

  NP_004957

• Overview:

  Recombinant protein of human heterogeneous nuclear ribonucleoprotein F (HNRNPF), transcript variant 3

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/3185

• Uniprot URL:

  https://www.uniprot.org/uniprot/P52597

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_004966

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_004957