VPS26 (VPS26A) (NM_004896) Human Recombinant Protein

• Background:

  This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

• Synonyms:

  HB58; Hbeta58; PEP8A; VPS26

• Gene ID:

  9559

• UniProt:

  O75436

• Accession Number mRNA:

  NM_004896

• Chromosomal Location:

  10q22.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  38 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  VPS26A

• Species:

  Human

• Protein ID:

  NP_004887

• Overview:

  Recombinant protein of human vacuolar protein sorting 26 homolog A (S. pombe) (VPS26A), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/9559

• Uniprot URL:

  https://www.uniprot.org/uniprot/O75436

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_004896

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_004887