KPNA4 (NM_002268) Human Recombinant Protein

• Background:

  The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs) . Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. [provided by RefSeq, Jul 2008]

• Synonyms:

  IPOA3; QIP1; SRP3

• Gene ID:

  3840

• UniProt:

  O00629

• Accession Number mRNA:

  NM_002268

• Chromosomal Location:

  3q25.33

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  57.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  KPNA4

• Species:

  Human

• Protein ID:

  NP_002259

• Overview:

  Recombinant protein of human karyopherin alpha 4 (importin alpha 3) (KPNA4)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/3840

• Uniprot URL:

  https://www.uniprot.org/uniprot/O00629

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_002268

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_002259