PGM1 (NM_002633) Human Recombinant Protein

• Background:

  The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Mar 2010]

• Synonyms:

  CDG1T; GSD14

• Gene ID:

  5236

• UniProt:

  P36871

• Accession Number mRNA:

  NM_002633

• Chromosomal Location:

  1p31.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Amino sugar and nucleotide sugar metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Pentose phosphate pathway, Starch and sucrose metabolism

• Field of Research:

  Amino sugar and nucleotide sugar metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Pentose phosphate pathway, Starch and sucrose metabolism

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  61.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  PGM1

• Species:

  Human

• Protein ID:

  NP_002624

• Overview:

  Recombinant protein of human phosphoglucomutase 1 (PGM1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/5236

• Uniprot URL:

  https://www.uniprot.org/uniprot/P36871

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_002633

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_002624