TUG (ASPSCR1) (NM_024083) Human Recombinant Protein

• Background:

  The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4) . This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t (X;17) (p11; q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Oct 2011]

• Synonyms:

  ASPCR1; ASPL; ASPS; RCC17; TUG; UBXD9; UBXN9

• Gene ID:

  79058

• UniProt:

  Q9BZE9

• Accession Number mRNA:

  NM_024083

• Chromosomal Location:

  17q25.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  60 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  ASPSCR1

• Species:

  Human

• Protein ID:

  NP_076988

• Overview:

  Recombinant protein of human alveolar soft part sarcoma chromosome region, candidate 1 (ASPSCR1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/79058

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9BZE9

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_024083

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_076988