CPSF73 (CPSF3) (NM_016207) Human Recombinant Protein

• Background:

  This gene encodes a member of the metallo-beta-lactamase family. The encoded protein is a 73kDa subunit of the cleavage and polyadenylation specificity factor and functions as an endonuclease that recognizes the pre-mRNA 3'-cleavage site AAUAAA prior to polyadenylation. It also cleaves after the pre-mRNA sequence ACCCA during histone 3'-end pre-mRNA processing. [provided by RefSeq, Oct 2012]

• Synonyms:

  CPSF-73; CPSF73

• Gene ID:

  51692

• UniProt:

  Q9UKF6

• Accession Number mRNA:

  NM_016207

• Chromosomal Location:

  2p25.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  77.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CPSF3

• Species:

  Human

• Protein ID:

  NP_057291

• Overview:

  Recombinant protein of human cleavage and polyadenylation specific factor 3, 73kDa (CPSF3)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/51692

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UKF6

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_016207

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_057291