Ribophorin II (RPN2) (NM_002951) Human Recombinant Protein

• Background:

  This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein is similar in sequence to the yeast oligosaccharyl transferase subunit SWP1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

• Synonyms:

  RIBIIR; RPN-II; RPNII; SWP1

• Gene ID:

  6185

• UniProt:

  P04844

• Accession Number mRNA:

  NM_002951

• Chromosomal Location:

  20q11.23

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Metabolic pathways, N-Glycan biosynthesis

• Field of Research:

  Metabolic pathways, N-Glycan biosynthesis

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Transmembrane

• Molecular Weight:

  67 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  RPN2

• Species:

  Human

• Protein ID:

  NP_002942

• Overview:

  Recombinant protein of human ribophorin II (RPN2), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/6185

• Uniprot URL:

  https://www.uniprot.org/uniprot/P04844

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_002951

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_002942