M-CSF (CSF1) (NM_172212) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]

• Synonyms:

  CSF-1; MCSF

• Gene ID:

  1435

• UniProt:

  P09603, A0A024R0A1

• Accession Number mRNA:

  NM_172212

• Chromosomal Location:

  1p13.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Cytokine-cytokine receptor interaction, Hematopoietic cell lineage

• Field of Research:

  Cytokine-cytokine receptor interaction, Hematopoietic cell lineage

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane

• Molecular Weight:

  59.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CSF1

• Species:

  Human

• Protein ID:

  NP_757351

• Overview:

  Recombinant protein of human colony stimulating factor 1 (macrophage) (CSF1), transcript variant 4

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/1435

• Uniprot URL:

  https://www.uniprot.org/uniprot/P09603

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_172212

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_757351