GAS2 (NM_177553) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2017]

• Synonyms:

  GAS-2; MGC32610

• Gene ID:

  2620

• UniProt:

  O43903

• Accession Number mRNA:

  NM_177553

• Chromosomal Location:

  11p14.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  34.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  GAS2

• Species:

  Human

• Protein ID:

  NP_808221

• Overview:

  Recombinant protein of human growth arrest-specific 2 (GAS2), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/2620

• Uniprot URL:

  https://www.uniprot.org/uniprot/O43903

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_177553

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_808221