MAP4K5 (NM_198794) Human Recombinant Protein

• Background:

  This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  GCKR; KHS; KHS1; MAPKKKK5

• Gene ID:

  11183

• UniProt:

  Q9Y4K4, B3KWC4

• Accession Number mRNA:

  NM_198794

• Chromosomal Location:

  14q22.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Protein Kinase

• Molecular Weight:

  94.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  MAP4K5

• Species:

  Human

• Protein ID:

  NP_942089

• Overview:

  Recombinant protein of human mitogen-activated protein kinase kinase kinase kinase 5 (MAP4K5), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/11183

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Y4K4

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_198794

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_942089