EXOSC1 (NM_016046) Human Recombinant Protein

• Background:

  This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly (A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2016]

• Synonyms:

  CGI-108; CSL4; Csl4p; p13; PCH1F; SKI4; Ski4p

• Gene ID:

  51013

• UniProt:

  Q9Y3B2

• Accession Number mRNA:

  NM_016046

• Chromosomal Location:

  10q24.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  RNA degradation

• Field of Research:

  RNA degradation

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  21.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  EXOSC1

• Species:

  Human

• Protein ID:

  NP_057130

• Overview:

  Recombinant protein of human exosome component 1 (EXOSC1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/51013

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Y3B2

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_016046

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_057130