RBFOX2 (NM_001031695) Human Recombinant Protein

• Background:

  This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  DJ106I20.3; Fox-2; FOX2; fxh; HNRBP2; HRNBP2; RBM9; RTA

• Gene ID:

  23543

• UniProt:

  O43251

• Accession Number mRNA:

  NM_001031695

• Chromosomal Location:

  22q12.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Transcription Factors

• Molecular Weight:

  40.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  RBFOX2

• Species:

  Human

• Protein ID:

  NP_001026865

• Overview:

  Purified recombinant protein of Homo sapiens RNA binding motif protein 9 (RBM9), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/23543

• Uniprot URL:

  https://www.uniprot.org/uniprot/O43251

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001031695

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001026865