Hexokinase Type III (HK3) (NM_002115) Human Recombinant Protein

• Background:

  Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate. [provided by RefSeq, Apr 2009]

• Synonyms:

  HKIII; HXK3

• Gene ID:

  3101

• UniProt:

  P52790, A0A024R7R1

• Accession Number mRNA:

  NM_002115

• Chromosomal Location:

  5q35.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Starch and sucrose metabolism, Type II diabetes mellitus

• Field of Research:

  Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Starch and sucrose metabolism, Type II diabetes mellitus

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  98.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  HK3

• Species:

  Human

• Protein ID:

  NP_002106

• Overview:

  Recombinant protein of human hexokinase 3 (white cell) (HK3), nuclear gene encoding mitochondrial protein

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/3101

• Uniprot URL:

  https://www.uniprot.org/uniprot/P52790

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_002115

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_002106