P75 NGF Receptor (NGFR) (NM_002507) Human Recombinant Protein

• Background:

  Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [provided by RefSeq, Jul 2008]

• Synonyms:

  CD271; Gp80-LNGFR; p75 (NTR) ; p75NTR; TNFRSF16

• Gene ID:

  4804

• UniProt:

  P08138

• Accession Number mRNA:

  NM_002507

• Chromosomal Location:

  17q21.33

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Cytokine-cytokine receptor interaction, Neurotrophin signaling pathway

• Field of Research:

  Cytokine-cytokine receptor interaction, Neurotrophin signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Transmembrane

• Molecular Weight:

  42.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  NGFR

• Species:

  Human

• Protein ID:

  NP_002498

• Overview:

  Recombinant protein of human nerve growth factor receptor (TNFR superfamily, member 16) (NGFR)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/4804

• Uniprot URL:

  https://www.uniprot.org/uniprot/P08138

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_002507

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_002498