N WASP (WASL) (NM_003941) Human Recombinant Protein

• Background:

  This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension. [provided by RefSeq, Jul 2013]

• Synonyms:

  N-WASP; NWASP; WASPB

• Gene ID:

  8976

• UniProt:

  O00401

• Accession Number mRNA:

  NM_003941

• Chromosomal Location:

  7q31.32

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Adherens junction, Chemokine signaling pathway, Fc gamma R-mediated phagocytosis, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton

• Field of Research:

  Adherens junction, Chemokine signaling pathway, Fc gamma R-mediated phagocytosis, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  54.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  WASL

• Species:

  Human

• Protein ID:

  NP_003932

• Overview:

  Recombinant protein of human Wiskott-Aldrich syndrome-like (WASL)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/8976

• Uniprot URL:

  https://www.uniprot.org/uniprot/O00401

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003941

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003932