Solo (SESTD1) (NM_178123) Human Recombinant Protein

• Background:

  May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  SOLO

• Gene ID:

  91404

• UniProt:

  Q86VW0, B3KTX3

• Accession Number mRNA:

  NM_178123

• Chromosomal Location:

  2q31.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  79.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  SESTD1

• Species:

  Human

• Protein ID:

  NP_835224

• Overview:

  Recombinant protein of human SEC14 and spectrin domains 1 (SESTD1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/91404

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q86VW0

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_178123

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_835224