Peptide YY (PYY) (NM_004160) Human Recombinant Protein

• Background:

  This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded preproprotein is proteolytically processed to generate two alternative peptide products that differ in length by three amino acids. These peptides, secreted by endocrine cells in the gut, exhibit different binding affinities for each of the neuropeptide Y receptors. Binding of the encoded peptides to these receptors mediates regulation of pancreatic secretion, gut mobility and energy homeostasis. Rare variations in this gene could increase susceptibility to obesity and elevated serum levels of the encoded peptides may be associated with anorexia nervosa. [provided by RefSeq, Feb 2016]

• Synonyms:

  PYY-I; PYY1

• Gene ID:

  5697

• UniProt:

  P10082

• Accession Number mRNA:

  NM_004160

• Chromosomal Location:

  17q21.31

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Secreted Protein, Transmembrane

• Molecular Weight:

  11 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  PYY

• Species:

  Human

• Protein ID:

  NP_004151

• Overview:

  Recombinant protein of human peptide YY (PYY)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/5697

• Uniprot URL:

  https://www.uniprot.org/uniprot/P10082

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_004160

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_004151