Eph receptor B3 (EPHB3) (NM_004443) Human Recombinant Protein

• Background:

  Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members. [provided by RefSeq, Mar 2010]

• Synonyms:

  EK2; ETK2; HEK2; TYRO6

• Gene ID:

  2049

• UniProt:

  P54753

• Accession Number mRNA:

  NM_004443

• Chromosomal Location:

  3q27.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Axon guidance

• Field of Research:

  Axon guidance

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Protein Kinase, Transmembrane

• Molecular Weight:

  106.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  EPHB3

• Species:

  Human

• Protein ID:

  NP_004434

• Overview:

  Recombinant protein of human EPH receptor B3 (EPHB3)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/2049

• Uniprot URL:

  https://www.uniprot.org/uniprot/P54753

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_004443

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_004434