FBXO4 (NM_012176) Human Recombinant Protein

• Background:

  This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

• Synonyms:

  FBX4

• Gene ID:

  26272

• UniProt:

  Q9UKT5, B3KNA0

• Accession Number mRNA:

  NM_012176

• Chromosomal Location:

  5p13.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Ubiquitin mediated proteolysis

• Field of Research:

  Ubiquitin mediated proteolysis

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  44 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  FBXO4

• Species:

  Human

• Protein ID:

  NP_036308

• Overview:

  Recombinant protein of human F-box protein 4 (FBXO4), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/26272

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UKT5

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_012176

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_036308