PARVB (NM_013327) Human Recombinant Protein

• Background:

  This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]

• Synonyms:

  CGI-56

• Gene ID:

  29780

• UniProt:

  Q9HBI1

• Accession Number mRNA:

  NM_013327

• Chromosomal Location:

  22q13.31

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Focal adhesion

• Field of Research:

  Focal adhesion

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  41.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  PARVB

• Species:

  Human

• Protein ID:

  NP_037459

• Overview:

  Recombinant protein of human parvin, beta (PARVB), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/29780

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9HBI1

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_013327

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_037459