Synaptotagmin V (SYT5) (NM_003180) Human Recombinant Protein

• Background:

  Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 [PubMed 7597049]) .[supplied by OMIM, Feb 2011]

• Synonyms:

  Synaptotagmin 5; synaptotagmin V

• Gene ID:

  6861

• UniProt:

  O00445, A0A024R4N8

• Accession Number mRNA:

  NM_003180

• Chromosomal Location:

  11p

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Secreted Protein, Transmembrane

• Molecular Weight:

  42.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  SYT5

• Species:

  Human

• Protein ID:

  NP_003171

• Overview:

  Recombinant protein of human synaptotagmin V (SYT5)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/6861

• Uniprot URL:

  https://www.uniprot.org/uniprot/O00445

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003180

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003171