FUCA2 (NM_032020) Human Recombinant Protein

• Background:

  This gene encodes a plasma alpha-L-fucosidase, which represents 10-20% of the total cellular fucosidase activity. The protein is a member of the glycosyl hydrolase 29 family, and catalyzes the hydrolysis of the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. This enzyme is essential for Helicobacter pylori adhesion to human gastric cancer cells. [provided by RefSeq, Aug 2010]

• Synonyms:

  DJ20N2.5

• Gene ID:

  2519

• UniProt:

  Q9BTY2

• Accession Number mRNA:

  NM_032020

• Chromosomal Location:

  6q24.2

• Expression System:

  HEK293

• Tag:

  C-Myc/DDK

• Related Pathways:

  Other glycan degradation

• Field of Research:

  Other glycan degradation

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Function:

  Druggable Genome, Secreted Protein

• Molecular Weight:

  53.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  FUCA2

• Species:

  Human

• Protein ID:

  NP_114409

• Overview:

  Purified recombinant protein of Human fucosidase, alpha-L- 2, plasma (FUCA2), full length, with C-terminal MYC/DDK tag, expressed in HEK293 cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/2519

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9BTY2

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_032020

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_114409