ROR beta (RORB) (NM_006914) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm. [provided by RefSeq, Feb 2014]

• Synonyms:

  BA133M9.1; EIG15; NR1F2; ROR-BETA; RZR-BETA; RZRB

• Gene ID:

  6096

• UniProt:

  Q58EY0

• Accession Number mRNA:

  NM_006914

• Chromosomal Location:

  9q21.13

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

• Molecular Weight:

  51.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  RORB

• Species:

  Human

• Protein ID:

  NP_008845

• Overview:

  Recombinant protein of human RAR-related orphan receptor B (RORB)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/6096

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q58EY0

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_006914

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_008845