ANGPTL3 (NM_014495) Human Recombinant Protein

• Background:

  This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2. [provided by RefSeq, Aug 2015]

• Synonyms:

  ANG-5; ANGPT5; ANL3; FHBL2

• Gene ID:

  27329

• UniProt:

  Q9Y5C1

• Accession Number mRNA:

  NM_014495

• Chromosomal Location:

  1p31.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Secreted Protein

• Molecular Weight:

  51.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  ANGPTL3

• Species:

  Human

• Protein ID:

  NP_055310

• Overview:

  Recombinant protein of human angiopoietin-like 3 (ANGPTL3)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/27329

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Y5C1

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_014495

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_055310