Carabin (TBC1D10C) (NM_198517) Human Recombinant Protein

• Background:

  The protein encoded by this gene has an N-terminal Rab-GTPase domain and a binding site at the C-terminus for calcineurin, and is an inhibitor of both the Ras signaling pathway and calcineurin, a phosphatase regulated by calcium and calmodulin. Genes encoding similar proteins are located on chromosomes 16 and 22. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013]

• Synonyms:

  CARABIN; EPI64C

• Gene ID:

  374403

• UniProt:

  Q8IV04

• Accession Number mRNA:

  NM_198517

• Chromosomal Location:

  11q13.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  49.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TBC1D10C

• Species:

  Human

• Protein ID:

  NP_940919

• Overview:

  Recombinant protein of human TBC1 domain family, member 10C (TBC1D10C)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/374403

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8IV04

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_198517

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_940919