AER61 (EOGT) (NM_173654) Human Recombinant Protein

• Background:

  This gene encodes an enzyme that acts in the lumen of the endoplasmic reticulum to catalyze the transfer of N-acetylglucosamine to serine or threonine residues of extracellular-targeted proteins. This enzyme modifies proteins containing eukaryotic growth factor (EGF) -like domains, including the Notch receptor, thereby regulating developmental signalling. Mutations in this gene have been observed in individuals with Adams-Oliver syndrome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

• Synonyms:

  AER61; AOS4; C3orf64; EOGT1

• Gene ID:

  285203

• UniProt:

  Q5NDL2

• Accession Number mRNA:

  NM_173654

• Chromosomal Location:

  3p14.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  52.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  EOGT

• Species:

  Human

• Protein ID:

  NP_775925

• Overview:

  Recombinant protein of human chromosome 3 open reading frame 64 (C3orf64)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/285203

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q5NDL2

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_173654

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_775925