THEM4 (NM_053055) Human Recombinant Protein

• Background:

  Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas. [provided by RefSeq, Jul 2008]

• Synonyms:

  CTMP

• Gene ID:

  117145

• UniProt:

  Q5T1C6, A8K0C9

• Accession Number mRNA:

  NM_053055

• Chromosomal Location:

  1q21.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  26.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  THEM4

• Species:

  Human

• Protein ID:

  NP_444283

• Overview:

  Recombinant protein of human thioesterase superfamily member 4 (THEM4)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/117145

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q5T1C6

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_053055

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_444283