TCTN1 (NM_001082537) Human Recombinant Protein

• Background:

  This gene encodes a member of a family of secreted and transmembrane proteins. The orthologous gene in mouse functions downstream of smoothened and rab23 to modulate hedgehog signal transduction. This protein is a component of the tectonic-like complex, which forms a barrier between the ciliary axoneme and the basal body. A mutation in this gene was found in a family with Joubert syndrome-13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

• Synonyms:

  JBTS13; TECT1

• Gene ID:

  79600

• UniProt:

  Q2MV58, B4DIB9

• Accession Number mRNA:

  NM_001082537

• Chromosomal Location:

  12q24.11

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Secreted Protein

• Molecular Weight:

  63.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TCTN1

• Species:

  Human

• Protein ID:

  NP_001076006

• Overview:

  Recombinant protein of human tectonic family member 1 (TCTN1), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/79600

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q2MV58

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001082537

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001076006