USP3 (NM_006537) Human Recombinant Protein

• Background:

  Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  SIH003; UBP

• Gene ID:

  9960

• UniProt:

  Q9Y6I4

• Accession Number mRNA:

  NM_006537

• Chromosomal Location:

  15q22.31

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Protease

• Molecular Weight:

  58.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  USP3

• Species:

  Human

• Protein ID:

  NP_006528

• Overview:

  Recombinant protein of human ubiquitin specific peptidase 3 (USP3)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/9960

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Y6I4

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_006537

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_006528