GRP94 (HSP90B1) (NM_003299) Human Recombinant Protein

• Background:

  This gene encodes a member of a family of adenosine triphosphate (ATP) -metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15. [provided by RefSeq, Aug 2012]

• Synonyms:

  ECGP; GP96; GRP94; HEL-S-125m; HEL35; TRA1

• Gene ID:

  7184

• UniProt:

  P14625, V9HWP2

• Accession Number mRNA:

  NM_003299

• Chromosomal Location:

  12q23.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  NOD-like receptor signaling pathway, Pathways in cancer, Prostate cancer

• Field of Research:

  NOD-like receptor signaling pathway, Pathways in cancer, Prostate cancer

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  90.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  HSP90B1

• Species:

  Human

• Protein ID:

  NP_003290

• Overview:

  Recombinant protein of human heat shock protein 90kDa beta (Grp94), member 1 (HSP90B1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/7184

• Uniprot URL:

  https://www.uniprot.org/uniprot/P14625

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003299

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003290