TYW3 (NM_138467) Human Recombinant Protein

• Background:

  Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006) .[supplied by OMIM, Mar 2008]

• Synonyms:

  C1orf171

• Gene ID:

  127253

• UniProt:

  Q6IPR3

• Accession Number mRNA:

  NM_138467

• Chromosomal Location:

  1p31.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  29.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TYW3

• Species:

  Human

• Protein ID:

  NP_612476

• Overview:

  Recombinant protein of human tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) (TYW3)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/127253

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q6IPR3

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_138467

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_612476