TSC22D3 (NM_004089) Human Recombinant Protein

• Background:

  This gene encodes the anti-inflammatory protein glucocorticoid (GC) -induced leucine zipper. Expression of this gene stimulated by glucocorticoids and interleukin 10 and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid. This protein has also been shown to inhibit pro-inflammatory molecules including nuclear factor κ B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

• Synonyms:

  DIP; DSIPI; GILZ; TSC-22R

• Gene ID:

  1831

• UniProt:

  Q99576

• Accession Number mRNA:

  NM_004089

• Chromosomal Location:

  Xq22.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Transcription Factors

• Molecular Weight:

  14.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TSC22D3

• Species:

  Human

• Protein ID:

  NP_004080

• Overview:

  Recombinant protein of human TSC22 domain family, member 3 (TSC22D3), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/1831

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q99576

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_004089

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_004080