HMGCS1 (NM_002130) Human Recombinant Protein

• Background:

  This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  HMGCS

• Gene ID:

  3157

• UniProt:

  Q01581, A0A024R059

• Accession Number mRNA:

  NM_002130

• Chromosomal Location:

  5p12

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Butanoate metabolism, Metabolic pathways, Synthesis and degradation of ketone bodies, Terpenoid backbone biosynthesis, Valine, leucine and isoleucine degradation

• Field of Research:

  Butanoate metabolism, Metabolic pathways, Synthesis and degradation of ketone bodies, Terpenoid backbone biosynthesis, Valine, leucine and isoleucine degradation

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  57.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  HMGCS1

• Species:

  Human

• Protein ID:

  NP_002121

• Overview:

  Recombinant protein of human 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) (HMGCS1), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/3157

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q01581

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_002130

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_002121