PDE7B (NM_018945) Human Recombinant Protein

• Background:

  The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.[provided by RefSeq, Apr 2009]

• Synonyms:

  BA472E5.1

• Gene ID:

  27115

• UniProt:

  Q9NP56

• Accession Number mRNA:

  NM_018945

• Chromosomal Location:

  6q23.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Progesterone-mediated oocyte maturation, Purine metabolism

• Field of Research:

  Progesterone-mediated oocyte maturation, Purine metabolism

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  51.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  PDE7B

• Species:

  Human

• Protein ID:

  NP_061818

• Overview:

  Recombinant protein of human phosphodiesterase 7B (PDE7B)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/27115

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9NP56

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_018945

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_061818