TRPC3 (NM_003305) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

• Synonyms:

  SCA41; TRP3

• Gene ID:

  7222

• UniProt:

  Q13507

• Accession Number mRNA:

  NM_003305

• Chromosomal Location:

  4q27

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane

• Molecular Weight:

  97.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TRPC3

• Species:

  Human

• Protein ID:

  NP_003296

• Overview:

  Recombinant protein of human transient receptor potential cation channel, subfamily C, member 3 (TRPC3), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/7222

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q13507

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003305

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003296