MST1 (STK4) (NM_006282) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq, Jul 2008]

• Synonyms:

  KRS2; MST1; TIIAC; YSK3

• Gene ID:

  6789

• UniProt:

  Q13043

• Accession Number mRNA:

  NM_006282

• Chromosomal Location:

  20q13.12

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  MAPK signaling pathway, Non-small cell lung cancer, Pathways in cancer

• Field of Research:

  MAPK signaling pathway, Non-small cell lung cancer, Pathways in cancer

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Protein Kinase

• Molecular Weight:

  55.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  STK4

• Species:

  Human

• Protein ID:

  NP_006273

• Overview:

  Recombinant protein of human serine/threonine kinase 4 (STK4)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/6789

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q13043

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_006282

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_006273