Glycogen synthase 2 (GYS2) (NM_021957) Human Recombinant Protein

• Background:

  The protein encoded by this gene, liver glycogen synthase, catalyzes the rate-limiting step in the synthesis of glycogen - the transfer of a glucose molecule from UDP-glucose to a terminal branch of the glycogen molecule. Mutations in this gene cause glycogen storage disease type 0 (GSD-0) - a rare type of early childhood fasting hypoglycemia with decreased liver glycogen content. [provided by RefSeq, Dec 2009]

• Synonyms:

  Glycogen synthase 2 (liver)

• Gene ID:

  2998

• UniProt:

  P54840

• Accession Number mRNA:

  NM_021957

• Chromosomal Location:

  12p12.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Insulin signaling pathway, Starch and sucrose metabolism

• Field of Research:

  Insulin signaling pathway, Starch and sucrose metabolism

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  80.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  GYS2

• Species:

  Human

• Protein ID:

  NP_068776

• Overview:

  Recombinant protein of human glycogen synthase 2 (liver) (GYS2)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/2998

• Uniprot URL:

  https://www.uniprot.org/uniprot/P54840

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_021957

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_068776