SOX6 (NM_017508) Human Recombinant Protein

• Background:

  This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]

• Synonyms:

  HSSOX6; SOXD; TOLCAS

• Gene ID:

  55553

• UniProt:

  P35712

• Accession Number mRNA:

  NM_017508

• Chromosomal Location:

  11p15.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Transcription Factors

• Molecular Weight:

  89.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  SOX6

• Species:

  Human

• Protein ID:

  NP_059978

• Overview:

  Recombinant protein of human SRY (sex determining region Y) -box 6 (SOX6), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/55553

• Uniprot URL:

  https://www.uniprot.org/uniprot/P35712

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_017508

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_059978