Collagen X (COL10A1) (NM_000493) Human Recombinant Protein

• Background:

  This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD) . [provided by RefSeq, Jul 2008]

• Synonyms:

  Collagen, type X, alpha 1; collagen X, alpha-1 polypeptide; OTTHUMP00000017049; OTTHUMP00000040411; Schmid metaphyseal chondrodysplasia; type X collagen alpha 1

• Gene ID:

  1300

• UniProt:

  Q03692

• Accession Number mRNA:

  NM_000493

• Chromosomal Location:

  6q22.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  64.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  COL10A1

• Species:

  Human

• Protein ID:

  NP_000484

• Overview:

  Recombinant protein of human collagen, type X, alpha 1 (COL10A1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/1300

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q03692

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_000493

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_000484