SIL1 (NM_022464) Human Recombinant Protein

• Background:

  This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]

• Synonyms:

  BAP; MSS; ULG5

• Gene ID:

  64374

• UniProt:

  Q9H173, A0A0S2Z6B4

• Accession Number mRNA:

  NM_022464

• Chromosomal Location:

  5q31.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Protease, Secreted Protein, Transmembrane

• Molecular Weight:

  48.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  SIL1

• Species:

  Human

• Protein ID:

  NP_071909

• Overview:

  Recombinant protein of human SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae) (SIL1), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/64374

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9H173

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_022464

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_071909