Clusterin (CLU) (NM_001831) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.[provided by RefSeq, May 2011]

• Synonyms:

  AAG4; APO-J; APOJ; CLI; CLU1; CLU2; KUB1; NA1/NA2; SGP-2; SGP2; SP-40; TRPM-2; TRPM2

• Gene ID:

  1191

• UniProt:

  P10909

• Accession Number mRNA:

  NM_001831

• Chromosomal Location:

  8p21.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Activity:

  28103719

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Secreted Protein

• Molecular Weight:

  57.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CLU

• Species:

  Human

• Protein ID:

  NP_001822

• Overview:

  Recombinant protein of human clusterin (CLU), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/1191

• Uniprot URL:

  https://www.uniprot.org/uniprot/P10909

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001831

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001822