NPHS2 (NM_014625) Human Recombinant Protein

• Background:

  This gene encodes a protein that plays a role in the regulation of glomerular permeability. Mutations in this gene cause steroid-resistant nephrotic syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

• Synonyms:

  PDCN; SRN1

• Gene ID:

  7827

• UniProt:

  Q9NP85

• Accession Number mRNA:

  NM_014625

• Chromosomal Location:

  1q25.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Transmembrane

• Molecular Weight:

  42 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  NPHS2

• Species:

  Human

• Protein ID:

  NP_055440

• Overview:

  Recombinant protein of human nephrosis 2, idiopathic, steroid-resistant (podocin) (NPHS2)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/7827

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9NP85

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_014625

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_055440