HDAC7A (NM_016596) Human Recombinant Protein

• Background:

  Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  HD7; HD7A; HDAC7A

• Gene ID:

  51564

• UniProt:

  Q8WUI4

• Accession Number mRNA:

  NM_016596

• Chromosomal Location:

  12q13.11

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Transcription Factors

• Molecular Weight:

  99.5

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  HDAC7A

• Species:

  Human

• Protein ID:

  NP_057680

• Overview:

  Recombinant protein of human histone deacetylase 7A (HDAC7A), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/51564

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8WUI4

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_016596

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_057680