VCAM1 (NM_080682) Human Recombinant Protein

• Background:

  This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]

• Synonyms:

  CD106; INCAM-100

• Gene ID:

  7412

• UniProt:

  P19320

• Accession Number mRNA:

  NM_080682

• Chromosomal Location:

  1p21.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Cell adhesion molecules (CAMs), Leukocyte transendothelial migration

• Field of Research:

  Cell adhesion molecules (CAMs), Leukocyte transendothelial migration

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

• Molecular Weight:

  68.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  VCAM1

• Species:

  Human

• Protein ID:

  NP_542413

• Overview:

  Recombinant protein of human vascular cell adhesion molecule 1 (VCAM1), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/7412

• Uniprot URL:

  https://www.uniprot.org/uniprot/P19320

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_080682

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_542413