Filensin (BFSP1) (NM_001195) Human Recombinant Protein

• Background:

  This gene encodes a lens-specific intermediate filament-like protein named filensin. The encoded protein is expressed in lens fiber cells after differentiation has begun. This protein functions as a component of the beaded filament which is a cytoskeletal structure found in lens fiber cells. Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

• Synonyms:

  CP94; CP115; CTRCT33; LIFL-H

• Gene ID:

  631

• UniProt:

  Q12934

• Accession Number mRNA:

  NM_001195

• Chromosomal Location:

  20p12.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  74.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  BFSP1

• Species:

  Human

• Protein ID:

  NP_001186

• Overview:

  Recombinant protein of human beaded filament structural protein 1, filensin (BFSP1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/631

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q12934

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001195

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001186