PPM1G (NM_177983) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. [provided by RefSeq, Apr 2010]

• Synonyms:

  PP2CG; PP2CGAMMA; PPP2CG

• Gene ID:

  5496

• UniProt:

  O15355, Q6IAU5

• Accession Number mRNA:

  NM_177983

• Chromosomal Location:

  2p23.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Activity:

  25658463

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Phosphatase

• Molecular Weight:

  59.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  PPM1G

• Species:

  Human

• Protein ID:

  NP_817092

• Overview:

  Recombinant protein of human protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform (PPM1G), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/5496

• Uniprot URL:

  https://www.uniprot.org/uniprot/O15355

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_177983

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_817092