ERC1 (NM_178040) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t (10;12) (q11; p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

• Synonyms:

  Cast2; ELKS; ERC-1; RAB6IP2

• Gene ID:

  23085

• UniProt:

  Q8IUD2

• Accession Number mRNA:

  NM_178040

• Chromosomal Location:

  12p13.33

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  127.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  ERC1

• Species:

  Human

• Protein ID:

  NP_829884

• Overview:

  Purified recombinant protein of Homo sapiens ELKS/RAB6-interacting/CAST family member 1 (ERC1), transcript variant epsilon

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/23085

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8IUD2

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_178040

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_829884