TBCE (NM_001079515) Human Recombinant Protein

• Background:

  Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  HRD; KCS; KCS1; pac2; PEAMO

• Gene ID:

  6905

• UniProt:

  Q15813

• Accession Number mRNA:

  NM_001079515

• Chromosomal Location:

  1q42.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  59.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TBCE

• Species:

  Human

• Protein ID:

  NP_001072983

• Overview:

  Recombinant protein of human tubulin folding cofactor E (TBCE), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/6905

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q15813

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001079515

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001072983