MTMR2 (NM_201281) Human Recombinant Protein

• Background:

  This gene is a member of the myotubularin family of phosphoinositide lipid phosphatases. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

• Synonyms:

  CMT4B; CMT4B1

• Gene ID:

  8898

• UniProt:

  Q13614, A0A024R3B7

• Accession Number mRNA:

  NM_201281

• Chromosomal Location:

  11q21

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Fructose and mannose metabolism, Metabolic pathways, Riboflavin metabolism, Thiamine metabolism

• Field of Research:

  Fructose and mannose metabolism, Metabolic pathways, Riboflavin metabolism, Thiamine metabolism

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Phosphatase

• Molecular Weight:

  65.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  MTMR2

• Species:

  Human

• Protein ID:

  NP_958438

• Overview:

  Recombinant protein of human myotubularin related protein 2 (MTMR2), transcript variant 3

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/8898

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q13614

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_201281

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_958438