Synaptojanin 2 (SYNJ2) (NM_003898) Human Recombinant Protein

• Background:

  The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

• Synonyms:

  INPP5H

• Gene ID:

  8871

• UniProt:

  O15056, B4DG94

• Accession Number mRNA:

  NM_003898

• Chromosomal Location:

  6q25.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system

• Field of Research:

  Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Phosphatase

• Molecular Weight:

  165.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  SYNJ2

• Species:

  Human

• Protein ID:

  NP_003889

• Overview:

  Recombinant protein of human synaptojanin 2 (SYNJ2)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/8871

• Uniprot URL:

  https://www.uniprot.org/uniprot/O15056

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003898

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003889